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chemical toxicity > chemical toxicity study 3


Chemical Toxicity Study #3

Title
Effect of Herbal Mixture Student Rasayana on Lipoxygenase Activity and Lipid Peroxidation

Publication
Free Radical Biology and Medicine, Vol. 18, No. 4, pp. 687-697, 1995.

Authors
Hari M. Sharma, Atef N. Hanna, Ellen M. Kauffman, and Howard A.I. Newman.

Conducted at
Department of Pathology, College of Medicine, The Ohio State University, Columbus, OH

Summary
Student Rasayana (SR) is an herbal mixture derived from the comprehensive system of natural health care known as Maharishi Ayurvedaa. SR has been reported to increase intelligence in children. This study was undertaken to evaluate the hypothesis that SR improves brain functioning by protecting the brain from free radical damage and/or increasing lipoxygenase activity associated with long-term potentiation (a process associated with memory). The in vivo portion of the study involved feeding rats a 2% (w:w) SR-supplemented diet for three weeks, then challenging their system with an intraperitoneal injection of toluene. The results showed that SR completely inhibited in vivo toluene-induced microsomal lipid peroxidation in rat brain microsomes (p<0.05).

For more information on this study, see Antioxidant Research and Research on Neurophysiology and Intelligence.


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