9:30am CST - 9:30 pm CST
Beta Version
|
chemotherapy toxicity > chemotherapy toxicity study 3
Chemotherapy Toxicity Study #3
Title
Protective Effects of MAK-4 and MAK-5 on Adriamycin-Induced Microsomal Lipid Peroxidation and Mortality
Publication
Biochemical Archives, Vol. 8, pp. 267-272, 1992.
Authors
Ferzaan N. Engineer,* Hari M. Sharma,** and Chandradhar Dwivedi.*
Conducted at
**College of Pharmacy, South Dakota State University, Brookings, SD
**College of Medicine, The Ohio State University, Columbus, OH
Summary
Use of the chemotherapeutic agent Adriamycin is complicated by its potentially lethal cardiac toxicity. DNA base pair damage induced by Adriamycin results in its effectiveness against cancer; however, simultaneous production of free radicals results in toxic side effects. In this study on mice, Adriamycin-induced mortality reached 60% in the control group (regular chow diet), compared to 20% in the group receiving a 6% MAK-4-supplemented diet (p<0.05), and 40% in the group receiving a 0.2% MAK-5-supplemented diet.
See Antioxidant Research for more information on this study.
|
Research Scientists: If you would be interested in doing research on any of our products please contact us at: questions@mapi.com
Give ayurveda information to a friend: Please do not reprint, or post on your website without written permission from MAPI. To obtain permission, please e-mail the webmaster at: questions@mapi.com. However, if you find our newsletter informative, we do give you permission to pass the newsletter on to a friend.
|
