Title
Antineoplastic Properties of Maharishi Amrit Kalash [MAK-5], An Ayurvedic Food Supplement, Against 7,12-Dimethylbenz(a)anthracene-Induced Mammary Tumors in Rats

Publication
Journal of Research and Education in Indian Medicine, Vol. 10, No. 3, pp. 1-8, July-September 1991.

Authors
Hari M. Sharma,* Chandradhar Dwivedi,** Bryan C. Satter,** and Hussein Abou-Issa.*

Conducted at
**College of Medicine, The Ohio State University, Columbus, OH 43210
**College of Pharmacy, South Dakota State University, Brookings, SD 57007

Summary

The herbal mixture Maharishi Amrit Kalash-5 (MAK-5) was tested for antineoplastic properties against 7,12-dimethylbenz(a)anthracene (DMBA)-induced mammary tumors in rats. The 0.2% (w/w) MAK-5-supplemented diet protected against DMBA-induced carcinogenesis during the promotion phase by reducing both tumor incidence and multiplicity. MAK-5 provided up to 62.5% protection (p<0.05) during the promotion phase of carcinogenesis. Also, a MAK-5-supplemented diet fed for four weeks to control rats which had developed mammary tumors, decreased tumor size in 60% of these rats.

There was no significant difference in weight gain in rats on the MAK-5-supplemented diet. Thus, the MAK-5-supplemented diet did not influence the food intake, but protected against DMBA-induced mammary tumors in rats.

Please Note

MAK-5 is now called Amrit Kalash Ambrosia.


Disclaimer
The sole purpose of these articles is to provide information about the tradition of ayurveda. This information is not intended for use in the diagnosis, treatment, cure or prevention of any disease. If you have any serious acute or chronic health concern, please consult a trained health professional who can fully assess your needs and address them effectively. If you are seeking the medical advice of a trained ayurvedic expert, call or e-mail us for the number of a physician in your area. Check with your doctor before taking herbs or using essential oils when pregnant or nursing.