Effects of a traditional herbal supplement on anxiety in patients with generalized anxiety disorder
Journal of Clinical Psychopharmacology 2002; 22 (4):443-444.
Mills, Paul J. PhD; Farag, Noha H. MD; Newton, Ruth P. PhD; Parry, Barbara L. MD
Department of Psychiatry; UCSD Medical Center; University of California, San Diego
Individuals diagnosed with general anxiety disorder were randomly assigned to receive either Worry Free or a placebo. After three months, those taking Worry Free showed significantly reduced general anxiety (trait anxiety), reduced anxiety in response to a challenging situation (public speech), and reduction in salivary cortisol (cortisol increases during stress).