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Title
Effects of a traditional herbal supplement on anxiety in patients with generalized anxiety disorder

Publication
Journal of Clinical Psychopharmacology 2002; 22 (4):443-444.

Authors
Mills, Paul J. PhD; Farag, Noha H. MD; Newton, Ruth P. PhD; Parry, Barbara L. MD

Conducted at
Department of Psychiatry; UCSD Medical Center; University of California, San Diego

Summary
Individuals diagnosed with general anxiety disorder were randomly assigned to receive either Worry Free or a placebo. After three months, those taking Worry Free showed significantly reduced general anxiety (trait anxiety), reduced anxiety in response to a challenging situation (public speech), and reduction in salivary cortisol (cortisol increases during stress).