In Vivo Effect of Herbal Mixture MAK-4 on Antioxidant Capacity of Brain Microsomes

Biochemical Archives, Vol. 12, pp. 181-186, 1996.

Hari M. Sharma, Jae Y. Lee, Ellen M. Kauffman, and Atef N. Hanna.

Conducted at
Department of Pathology, College of Medicine, The Ohio State University, Columbus, OH 43210


There is increasing evidence that free radicals are linked to neurological disorders and aging. This study examined the in vivo effect of MAK-4 on lipid peroxidation and antioxidant protection capacity of the brain of Watanabe Heritable Hyperlipidemic (WHHL) rabbits. Brain microsomes of rabbits fed MAK-4 showed significantly lower levels of lipid peroxidation than those of control rabbits fed normal chow. These results indicate MAK-4 may yield increased antioxidant protection in the brain, and may therefore be useful in preventing or treating free radical-induced neurological disorders.

For details of this study, see Antioxidant Research.

Please Note

MAK-4 is now called Amrit Kalash Nectar.

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