Antioxidant Properties of Two Ayurvedic Herbal Preparations [MAK-4 and MAK-5]

Biochemical Archives, Vol. 10, pp. 25-31, 1994.

Stephen C. Bondy, Tina M. Hernandez, and Cara Mattia.

Conducted at
Department of Community and Environmental Medicine, University of California (Irvine), Irvine, CA 92717


This study investigated the antioxidant effects of MAK-4 and MAK-5 in the rat brain in vitro and in vivo. In vitro, ethanol and aqueous extracts of MAK-4 and MAK-5 were able to quench generation of reactive oxygen species within an isolated fraction of rat cerebral cortex enriched in mitochondria and nerve endings (synaptosomes). In vivo, the excess production of reactive oxygen species observed within the cerebellar mitochondrial fraction after exposure of rats to toluene, was prevented by pretreatment with MAK-5.

For more information on this study, see Research on Reduction of Chemical Toxicity and Antioxidant Research.

Please Note

MAK-4 is now called Amrit Kalash Nectar.
MAK-5 is now called Amrit Kalash Ambrosia.

The sole purpose of these articles is to provide information about the tradition of ayurveda. This information is not intended for use in the diagnosis, treatment, cure or prevention of any disease. If you have any serious acute or chronic health concern, please consult a trained health professional who can fully assess your needs and address them effectively. If you are seeking the medical advice of a trained ayurvedic expert, call or e-mail us for the number of a physician in your area. Check with your doctor before taking herbs or using essential oils when pregnant or nursing.